Protective role of Ashwagandharishta and flax seed oil against maximal electroshock induced seizures in albino rats
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چکیده
منابع مشابه
Anticonvulsant Activity of Viola tricolor against Seizures Induced by Pentylenetetrazol and Maximal Electroshock in Mice
Background: Recently, there has been much more interest in the use of medicinal plants in search of novel therapies for human neurodegenerative diseases such as epilepsy. In the present study, we investigated the anticonvulsant effects of Viola tricolor (V. tricolor) on seizure models induced by pentylenetetrazol (PTZ) and maximal electroshock stimulation (MES). Methods: Totally, 260 mice were ...
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Background and Objective: Aging is a natural phenomenon which can cause changes in most organs and cells. Numerous mechanisms including oxidative stress and free radical generation is involved in the progression of the aging process. Pomegranate seed oil (PSO), has different therapeutic properties including anti-oxidant and anti-inflammatory effects. In this research, the effect of PSO against ...
متن کاملIndapamide enhances the protective action of carbamazepine, phenobarbital, and valproate against maximal electroshock-induced seizures in mice.
PURPOSE To determine the influence of indapamide on the protective action of numerous conventional and second-generation antiepileptic drugs (carbamazepine, lamotrigine, oxcarbazepine, phenobarbital, topiramate and valproate) in the mouse maximal electroshock seizure model. MATERIAL AND METHODS Electroconvulsions were evoked in Albino Swiss mice by a current (sine-wave, 0.2 s stimulus duratio...
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Background: Crude oil is a very toxic chemical. Recently, the search for protective substances is attracting attention. This study aimed to investigate the hematoprotective potentials of oil palm leaves against the toxicity induced by crude oil. Methods: Male Wistar albino rats (n=36) were divided into six groups of rats (n=6). Group 1 (controls) were fed with normal rat food. Groups 2 and ...
متن کاملEffects of some convulsant agents on the protective activity of topiramate against maximal electroshock-induced seizures in mice.
The anticonvulsant activity of topiramate combined with some convulsant agents (bicuculline--BIC, N-methyl-D-aspartate--NMDA, and kainic acid--KA), given at subconvulsive doses, was evaluated in the maximal electroshock (MES)-test in mice. BIC (1.5 mg/kg), KA (10 mg/kg) and NMDA (50 mg/kg) significantly decreased the anticonvulsant activity of topiramate raising its ED(50) from 76.2 mg/kg to 13...
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ژورنال
عنوان ژورنال: AYU (An International Quarterly Journal of Research in Ayurveda)
سال: 2012
ISSN: 0974-8520
DOI: 10.4103/0974-8520.100327